Case 15 — Comparison Case 2
Tilly was presented for a swollen mammary gland and cough. An arrhythmia was auscultated. Radiographs showed right heart enlargement typical of heartworm disease (antigen positive). She was treated with thiacetarsemide but treatment was inappropriately discontinued after one dose when ALT increased. Two months later at the VMTH for ovariohysterectomy, the arrhythmia persisted.
Diltiazem was titrated to 120 mg (3 mg/kg) q8h, which maintained sinus rhythm. Surgery was successful. Surprisingly, her heartworm antigen test was now negative and radiographs had improved, so adulticide retreatment was deferred.
At suture removal, the owner had decided not to continue diltiazem unless clinical signs appeared. The arrhythmia was still present at one and three years later, but she had no structural heart disease on echocardiogram at the three-year exam. The owner probably made the right decision.