Case 12 — Pleural Fluid

Lucky, a ten-year-old female spayed German shepherd cross.
Lucky — 10-year-old FS German shepherd cross, 17 kg.

Clinicians

Mark D. Kittleson, D.V.M., Ph.D., DACVIM (Cardiology)

Signalment

  • Species: Canine
  • Breed: German shepherd cross
  • Age: 10 years
  • Sex: Female spayed
  • Weight: 17 kg
  • Name: Lucky

Presenting Complaints

  • Fluid in the Chest / Possible Tumor

Pertinent History

  • Lucky was adopted at 6 months of age. She has lived in Fresno, CA and every summer goes to Fish Camp near Yosemite (alt = 5000′). This summer she did not go because the referring DVM advised against it.
  • Approximately 6 months ago, the owner noticed she was not eating as well, becoming lethargic, and panting more frequently. Three weeks ago she began refusing kibble.
  • Nine days ago she was taken to the emergency hospital for “gurgling” sounds. Radiographs revealed severe pleural effusion and possibly pulmonary edema. ECG showed tachycardia (HR = 270 bpm). 1500 ml of serosanguinous fluid was drained. She had a fever (105.0°F) and was mildly dehydrated. Fluid SG was 1.015, protein 1.0 g/dL (most consistent with a transudate). Sent home on Lasix 12.5 mg (1½ tabs SID), enalapril 20 mg (¼ tab q12h), and digoxin 0.125 mg (1½ tabs SID).
  • Yesterday she returned for “gurgling” sounds. 1500 ml of clear straw-colored fluid removed. Found 5% dehydrated. Digoxin reduced to 1 tab SID (0.125 mg). Referred to UC Davis.

Physical Examination

  • T = 101.5°F; HR = 240; RR = 52
  • QAR, mild dehydration, emaciated.
  • Integument: Full, dry, and coarse coat. No alopecia. Two ticks seen and removed.
  • Eyes: Clear corneas and anterior chambers; small amount of clear-greenish discharge OU. Ears: clean.
  • Nose: Moist, no discharge. Mouth: 4+ tartar with moderate gingivitis.
  • MS: Emaciated with general muscular atrophy. No gait abnormalities.
  • GI: Palpated a 2-cm soft mass in the ventral abdomen (may be fat or intestine). Hepatomegaly, small spleen.
  • GU: No vaginal discharge; empty bladder. Nervous: Not evaluated. LN: All WNL.
  • CV: Tachycardia fluctuating in rate and rhythm. No murmur auscultated. MM pink; CRT = 2 sec. Weak to fair pulses. Pulse deficits noted. Positive hepatojugular reflux test.
  • Respiratory: Dyspnea (panting and increased chest movements). Prefers to remain standing or sternal (orthopnea).

Problems

  • Dyspnea with historical pleural effusion
  • Positive hepatojugular reflux test
  • Emaciation
  • Tachycardia / Arrhythmia

Laboratory Work

  • Difil test for microfilariae — negative
  • Heartworm antigen test — negative